The joining of machine parts by plastic forming is a common method for transmitting forces and torque. In drive trains, the ‘knurled interference fit’ has a high transmission capacity through the combination of frictional connection and form fit. In the present study, the shaft specimen made of C45 steel material is joined with an inner knurled hub made of 16MnCr5 case hardened steel. The influence of the joining process parameters on the torsional fatigue strength of the shaft-hub connection is investigated by means of experimental studies. The most important parameter is the chamfer angle of the knurled hub, which determines the rate of strain hardening in the material and differs between the cutting and forming joining processes. This study shows that knurled interference fit connections joined by forming achieve a higher fatigue strength and a higher maximum static torque than connections joined by cutting.